Function Health Results: What 4 Rounds and 130 Biomarkers Showed

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Updated September 17, 2026

I have completed four rounds of Function Health blood testing since August 2024. This page is the data: 130 biomarkers on my most recent panel, a biological age of 37.3, a full hormone workup read through the menopausal transition and the one result that would have sent me to my doctor for unnecessary follow-up if I had only tested once.

Most write-ups of this service come from someone who tested a single time. Mine is four rounds over two years, by a woman in her fifties who lifts five days a week and has been on hormone replacement therapy. If you want the cost breakdown and whether the membership is worth buying, that lives in my is Function Health worth it analysis. This page answers a different question: what does the blood test actually measure, and what do the results look like when you run it four times?

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How the Function Health Blood Test Works

Once you enroll in Function Health (that link skips the waiting line), you schedule lab appointments at a local Quest Diagnostics location. Your first round requires two fasting visits. On my first visit they drew roughly 12 vials of blood and took a urine sample. They drew about the same amount at my second visit a couple of days later.

You need to complete both visits within 10 days, so plan accordingly. I have never had trouble getting early morning appointments about a week out at my Quest location near Cincinnati, though availability varies by area. There is no additional Quest draw fee in Ohio. Some states, notably New York and New Jersey, carry a higher membership price, so check what applies where you live before you sign up.

Preparation is straightforward: stop supplements 72 hours before, avoid seafood 48 hours before (you will be tested for mercury), fast for 8 hours and drink plenty of water the morning of your appointment. Continue any prescription medications as your doctor directs.

Your first draw runs the full panel of 100+ markers. Your follow-up draw a few months later repeats roughly 60 of them, the ones worth watching for movement rather than the full sweep. Function markets this as 160+ lab tests a year, which is accurate as a count of tests run, though it is not two identical 100-marker panels. On my dashboard the unique marker count sits at 130 because I have added several optional tests on top of the base panel.

One thing I did not know for my first two rounds: you are not limited to the two scheduled draws. You can re-test any single marker on demand for as little as $19. I work through that pricing and the full add-on menu in my Function Health cost breakdown.

What the Function Health Blood Test Includes

The base panel spans heart, liver, blood, metabolic, hormones, nutrients, thyroid, autoimmunity, kidney and heavy metals. Rather than list every marker, here is the full included test list.

This full panel tells you far more than a standalone perimenopause test, most of which say little on their own. If hormones are the reason you are considering testing, my perimenopause symptoms guide is the better place to start before you spend anything.

The Add-Ons I Have Paid For

Across four rounds I have added four tests. The ApoE test gives you your Alzheimer's risk genotype. I carry the ApoE 3/4 variant, which I have written about in my deep sleep article, so this was one I wanted immediately. The celiac panel covers celiac disease and gluten-related immune response, though you must have been eating gluten for the result to mean anything. The Omega panel covers EPA, DPA, DHA, total omega 6, arachidonic acid, total omega 3 and the omega 6 to omega 3 ratio, and it is the one I would repeat every round.

The big one was the Galleri multi-cancer early detection test at $749, which screens for over 50 cancer types from a single draw. Given how much cancer runs in my family, I added it and tested on July 10, 2025. The result came back “Cancer Signal Not Detected,” which was a relief. A negative Galleri is reassuring, not a guarantee, and it does not replace mammograms or colonoscopies. What I value is that Function makes a test most doctors would hesitate to order easy to access.

Add-Ons Worth Knowing About

Several optional tests answer questions readers ask me constantly, and none of them are in the base panel. Progesterone is available as a $19 add-on, which matters if you are tracking hormones through the transition and noticed it missing from the standard workup. There is a Mold and Environmental Toxin Response panel, and I cover what it does and does not measure further down, because the answer is more nuanced than yes or no.

Two more are interesting if you pay attention to what is in your kitchen and your water. Function offers a Forever Chemicals (PFAS) Exposure panel and a Bisphenol A (BPA) Exposure panel. PFAS turn up in nonstick cookware, food packaging, stain-resistant fabric and firefighting foam. If you have read my PFAS-free cookware coverage and wondered whether any of it shows up in your blood, those are the tests that would tell you. I have not run either one yet, so I cannot speak to the results firsthand. Every add-on price sits in my cost breakdown.

Function has also expanded past blood work. After acquiring the imaging company Ezra in 2025, they offer a full-body MRI as an add-on at $899 for the standard scan, with tiers that add spine imaging and a skeletal and neurological assessment, plus separate heart and lung CT scans. The MRI uses FDA-cleared AI and is designed to catch early signs of tumors, aneurysms and fatty liver before symptoms appear. You book through an Ezra account linked to your Function dashboard and results take about 7 to 10 days. I have not done the MRI, so that is research-based rather than something I can speak to. I will report back once I have.

How Long Function Health Results Take

Across four rounds the timing has been consistent enough that I can give you real numbers rather than the marketing estimate.

Results arrive in waves rather than all at once, which surprised me the first time. You will see a partial dashboard within two days and it fills in over the following week. If you are the kind of person who checks compulsively, know that a marker showing as pending is not a problem, it is a slower assay.

The clinician notes are the slowest piece and the part worth waiting for. They do not generate until your results are complete, because the whole point is that a clinician reads your markers together rather than one at a time.

My Function Health Results After 4 Rounds

Here is where this gets specific. A single round tells you where you stand today. Four rounds tell you which direction you are heading, and that trajectory is the thing almost no other write-up can show you.

My February 2026 dashboard shows 130 biomarkers: 89 in range, 19 out of range and 22 categorized as other, meaning they have no standard optimal range or need context to interpret.

Metabolic Markers

My metabolic markers are where I see the clearest payoff from years of eating low carb. Glucose came back at 86 mg/dL, HbA1c at 5.2% and insulin at 2.7 uIU/mL. My clinician notes called this out as outstanding blood sugar balance and very low risk for diabetes. Watching that same trio hold steady across four rounds, rather than reading it once, is what turns a lab result into confidence that the approach is working.

One marker flagged below range: leptin at 2.7 ng/mL. Leptin helps regulate appetite and energy balance and levels this low signal that energy stores are depleted. In my case that reflects low body fat from competitive bodybuilding. The foundational research in the New England Journal of Medicine measured leptin in 275 people and found a strong correlation between serum leptin and body fat percentage, so a low reading at low body fat is expected rather than alarming. It is also exactly the kind of nuance a standard annual physical would never surface.

Liver and Organ Function

My liver panel was mostly clean, with ALT at 18 U/L, albumin at 4.3 g/dL and GGT at 11 U/L. Alkaline phosphatase flagged at 35 U/L, below Function's optimal range. Low ALP is sometimes associated with zinc or magnesium insufficiency. My magnesium was in range at 5.7 mg/dL, so this is one I keep watching.

This section is also where repeat testing saved me money. One of my liver enzymes spiked after a hard leg session and looked alarming in isolation. Because I could watch it drop back to normal on the next draw, I avoided a round of follow-up testing and a month of worrying. A single one-time panel would have given me the scary number with no way to put it in context.

Nutrients

The nutrient panel covers things most doctors do not test. Homocysteine came back at 8.1 umol/L, ferritin at 53 ng/mL, iron at 81 mcg/dL and magnesium at 5.7 mg/dL, all in range. Function displays a small trend graph next to each marker so you can see the direction of travel at a glance, which is the feature I look forward to most with each round.

Hormones Through the Menopausal Transition

This is the section I wish more Function Health write-ups included. The base membership runs a full female hormone workup: estradiol, FSH, LH, testosterone total and free, DHEA-sulfate, SHBG, AMH and prolactin. For a woman moving through the menopausal transition these are the markers that shift and they are the ones a standard physical almost never runs together.

The reason trend data matters here more than a single reading is well documented. Research from the Study of Women's Health Across the Nation, published in the Journal of Clinical Endocrinology and Metabolism, identified four distinct estradiol trajectories and three distinct FSH trajectories through the transition, varying by body mass index and ethnicity. In other words there is no single normal curve to compare one reading against. Watching your own line over years tells you far more than any single draw measured against a population range.

I have an added complication that shapes how I read these numbers. I had a hysterectomy in 2007 at 33, with my ovaries preserved, so I have no menstrual markers to stage myself against. I have also been on hormone therapy since 2020. That combination means I cannot pinpoint exactly where I sit in the transition, and no test on the market will tell me. What repeat testing does give me is the shape of my own estradiol, FSH and testosterone lines over two years, which has been the most useful hormone information I have had.

Two honest limitations. Function draws on a scheduled lab day, not a specific cycle day, so if you need cycle-timed hormone testing to evaluate luteal phase progesterone, this is not a substitute and you should not buy it expecting one. And progesterone is not in the standard panel at all, though it is available as a $19 add-on if you want it alongside the rest.

The Cardiovascular Markers Most Panels Skip

This is the part of the panel I have come to value most. Alongside standard total, LDL and HDL cholesterol, Function runs ApoB, lipoprotein(a) and a full LDL particle breakdown including particle number, size and pattern.

That matters because standard LDL cholesterol is a weaker predictor than most people assume. A review in the Journal of the American Heart Association lays out the physiology behind why ApoB, which counts the actual number of atherogenic particles, predicts cardiovascular risk more accurately than the cholesterol mass those particles carry. A comparative review in the journal Pathology reached the same conclusion, noting that ApoB and non-HDL cholesterol are more accurate than LDL cholesterol in people with high triglycerides, in non-fasting samples and at very low LDL levels.

Lipoprotein(a) is largely genetic and you only need to measure it once, but most people never do because it is rarely ordered. If it is elevated, that is information worth having decades before it matters. Getting ApoB and Lp(a) inside a membership rather than arguing for them individually is, for me, one of the strongest arguments in Function's favor. Some competing services charge extra for Lp(a) and the particle breakdown, which I get into in my cost comparison.

My Biological Age Results

This is the number everyone wants to see. Based on my February 2026 testing, Function calculated my biological age at 37.3, which is 15.5 years younger than my calendar age. The calculation compares your biomarker results against population-level health data.

Is the metric perfect? No, and I want to be clear about that. Different platforms use different algorithms and produce different numbers from the same body. Around the same window, Function put me at 37.3, Hundred Health at 38.0 and Superpower at 45.2. That is an eight-year spread on one person tested within months. Treat the absolute figure as a motivational benchmark, not a clinical result.

What is worth tracking is the direction. Across my four rounds the number has stayed in a tight band, which is what I want to see: a biological age holding steady or ticking down while calendar age climbs. If it had jumped several years between rounds, that would be my cue to dig into which markers moved.

There is also a way to estimate this independently from labs you have already paid for. Every Function draw includes a complete blood count, and a 2026 machine learning study of more than 163,000 people, published in the American Journal of Preventive Cardiology, found that biological age estimated from routine CBC parameters independently predicted mortality and major cardiovascular events beyond chronological age. Red cell distribution width, mean cell volume and neutrophil count did most of the predictive work. I built a free biological age calculator on that protocol, so once your results land you can run your own CBC through it in about two minutes.

The Clinician Notes and Doctor Review

One of the most common questions I get is whether you get access to a real clinician. You do. After results complete, a licensed clinician reviews every biomarker and writes notes organized into strengths, areas to watch and specific recommendations.

My February 2026 notes highlighted that my red and white blood cell counts, hemoglobin, platelets and related indices had fully rebounded from prior lows, describing strong bone marrow recovery and good oxygen delivery for my activity level. That “rebounded from prior lows” language is only possible because the clinician can see my earlier rounds. On a first-round review, that context does not exist. This is the single clearest argument for staying past year one.

In an earlier round I also received a phone call from a Function clinician when a couple of results came back unexpected. They flagged it proactively and recommended I follow up with my primary care physician. That kind of response is not something most direct-to-consumer lab services offer.

This layer is the real separation between Function Health and ordering your own labs. Raw numbers tell you a value. The notes tell you what that value means alongside your other markers, what is reassuring and what is worth watching. Over four rounds I have come to rely on the interpretation as much as the numbers.

The Function AI Health Coach

Function has added an AI health coach that generates food and supplement recommendations from your biomarker results, sorting foods into enjoy, limit and avoid. In my case it flagged lipid abnormalities and built recommendations around lowering LDL and supporting healthy triglycerides.

This is the weakest part of the product. The recommendations are algorithmic and do not account for your dietary context. I have eaten low carb since 2017, and the AI told me to limit butter, coconut oil and full-fat cheese while my glucose, insulin and HbA1c all sit in the optimal range. An algorithm that cannot see that my metabolic panel is excellent should not be issuing confident dietary instructions. Use it as one data point and discuss real changes with your own provider.

What Function Health Does Not Test

Most write-ups bury this. Here is the honest list of what this blood test will not tell you, based on four rounds.

• No mycotoxins. This one needs care, because the answer changed. Function now sells a Mold and Environmental Toxin Response add-on, but it measures four inflammatory markers linked to Chronic Inflammatory Response Syndrome rather than mold itself. Function's own product description says it does not detect mold. It tells you whether your body appears to be reacting, not what you were exposed to, and it will not identify a species. For that you still need a dedicated mycotoxin urine panel elsewhere.
• No stool or gut pathogen panel. Parasites and microbiome work need a separate test. Function lists a gut health test as coming soon, so this may change.
• No cycle-timed hormone testing. Progesterone is not in the standard panel, and although you can add it for $19, draws happen on a scheduled lab day rather than a specific cycle day.
• No treatment or prescriptions. It is a testing platform, not a medical practice. An alarming result still sends you to your own doctor.
• No continuous data. Two draws a year is not wearable-level tracking, which is why I run this alongside an Oura Ring rather than instead of one.
• No sit-down consultation. The notes are written, not a conversation.
• Nothing beyond the base panel without paying more. Galleri at $749 and the full-body MRI at $899 can more than triple your annual spend.

Dr. Mark Hyman and the Functional Medicine Approach

Part of what separates Function Health from other lab services is the philosophy behind it. Dr. Mark Hyman, one of six co-founders, spent years as head of the Cleveland Clinic Center for Functional Medicine. His approach has always been about the whole picture rather than treating individual symptoms, and he is a 15-time New York Times bestselling author on diet, metabolism and longevity.

A lot of people find Function by searching for Dr. Mark Hyman's blood test or Dr. Hyman's labs, and that is a fair way to think about it. Function is the testing platform he co-founded to bring functional-medicine-style panels directly to people without a specialist referral for every marker. You are not booking an appointment with Dr. Hyman. What you are getting is a panel designed around the model he built his career on, reviewed by licensed clinicians.

That philosophy shows up in how Function defines optimal ranges. Rather than telling you whether a number falls inside the standard laboratory reference range (which is drawn from the general population, including plenty of unhealthy people), Function uses tighter ranges based on what research suggests is best for long-term health. This is why markers get flagged out of range on your Function dashboard that your regular doctor would call perfectly normal. It is a more preventive lens, and it can also generate anxiety if you are not expecting it.

What Reddit Users Are Saying About Function Health

Search Function Health on Reddit and you will find an active community on r/Function_Health plus discussions in r/Biohackers and r/HubermanLab. The sentiment is mixed, which is useful if you are researching.

One of the most upvoted r/Biohackers threads generated over 160 comments. The praise mirrors my experience: breadth of testing at this price point, an easy dashboard and clinician notes that add value beyond raw data. Several users named trend tracking over time as the biggest differentiator.

The criticisms deserve airing too. A thread titled “Took the leap. EXTREMELY disappointed” centers on add-on pricing, with users feeling the base panel is a starting point that requires expensive upgrades. Others report clinician notes reading generic or arriving slower than expected. A recurring theme is data overload, the sense that 100+ biomarkers without a physician to walk you through them feels overwhelming rather than empowering.

My take after four rounds: the overload criticism is fair if you do not already have some health literacy or a provider to discuss results with. If you are actively tracking your health and willing to learn, the volume of data is the point. The add-on pricing complaint is also fair, and it is why I broke every price out in my cost analysis rather than leaving people to find out at checkout.

How Function Health Compares to Other Blood Tests

I have tested Function alongside other platforms rather than in isolation, which is the context most single-service write-ups lack. I ran Superpower and Hundred Health on the same body within months of my Function panels, which is how I know the biological age numbers disagree by eight years.

For the head-to-head detail, my Function Health vs Superpower comparison walks through test selection, experience and results marker by marker, and my InsideTracker vs Function Health comparison covers how those two approaches differ. Pricing across all of them, including which service charges extra for markers Function includes, sits in my cost breakdown.

Who Should Test (and Who Should Skip It)

This blood test is a good fit if you want more data than a standard physical provides, have a family history of chronic disease and want early detection markers, are already working on nutrition or training and want to see whether it shows up in your labs, are comfortable reading data or have a provider to share results with, or care about tracking biological age and longevity markers over time.

Skip it if you get health anxiety from seeing results without a doctor to immediately explain them, want direct medical treatment or prescriptions, need someone to walk you through every number in person, only want one baseline panel rather than a tracking habit, or would stress about the annual cost more than you would benefit from the data.

After four rounds over two years, this has become one of the most useful health tools I own. It sits alongside my Oura Ring 4, Hume Band, Eight Sleep and Chilipad as part of how I monitor what is working. The wearables give me daily feedback. The blood test gives me the biomarker-level picture that confirms whether the daily choices are adding up.

The honest version: if you will test once and never again, buy a cheaper one-time panel instead. Everything that makes this worth the money comes from the second, third and fourth rounds, where the clinician can see your history and a scary-looking single result becomes a line on a graph. Whether that adds up for your budget is the question I work through in my is Function Health worth it breakdown.

If that is how you want to approach your health, use this link to skip the waitlist and save $25.