Hundred Health Review 2026: Worth the $499? My Honest Verdict
I got my blood drawn for Hundred Health on March 16, 2026. I was at Quest Diagnostics before 8 AM, fasted, and back home by 8:15. The whole appointment took maybe ten minutes. By the next morning, results were already rolling in: 48 biomarkers back from the lab within 24 hours, with more arriving throughout the day. This Hundred Health review covers my full experience so far, including onboarding, the medical records import, early lab results, and detailed research on the platform. I will continue updating this article as the remaining results and my 100-day protocol arrive.
I spend a lot of time in this space. I currently wear an Oura Ring 4, a Whoop, and a Hume Band simultaneously, so I have a fairly detailed picture of what my body is doing day to day. What I have always wanted to pair with that wearable data is a deep biomarker panel that goes well beyond what a standard annual physical covers. Hundred Health promises to deliver exactly that, connecting it all into one personalized action plan.
I have personally used and reviewed both Superpower Health and Function Health (and have compared them) so I am not coming to this cold. I have real benchmarks for what works and what falls short in this category. Hundred Health launched in December 2025 and positions itself as the most integrated option in the space and it's the only one offering a personalized 100 day protocol. I wanted to find out whether those claims holds up.
This review covers everything I know so far: how the onboarding and app work, the medical records integration that pulled in 21 years of my health history, early lab results including a couple of out-of-range findings, the complete biomarker panel, the premium add-ons (including some that matter a lot to me personally given my family health history), how Hundred compares to Function Health and Superpower, and whether the $499 annual membership is worth it. I will continue updating this article with additional results and my full 100-day protocol assessment as the data comes in.
Disclaimer: Links may contain affiliate links, which means we may get paid a commission at no additional cost to you if you purchase through this page. Read our full disclosure here.
Quick Verdict
Hundred Health is one of the most compelling entrants in the direct-to-consumer biomarker space. At $499 per year for 160+ lab tests across two draws, a clinician-reviewed 100-day protocol, and genuine wearable integration, the value is strong. The premium add-on menu, which includes the DUTCH Complete hormone panel and the Galleri multi-cancer early detection test, takes it further than most competitors can match. The app is clean and well-organized even in beta. My main caveat: the platform only launched three months ago, so long-term track record data does not exist yet. That said, I signed up, completed my first draw, and I am genuinely curious to see what this protocol delivers.
Bottom line: Solid platform, right price, right add-ons. Check current Hundred Health pricing and availability here.
Table of Contents: Click to Expand
- What Is Hundred Health?
- How Hundred Health Works
- What Does Hundred Health Test? The Full Panel
- Premium Add-Ons: Where It Gets Really Interesting
- My First Impressions: The App and Onboarding
- Medical Records Integration: 21 Years of Health History
- Early Results: What Came Back First
- Hundred Health Pros and Cons
- Hundred Health vs Function Health vs Superpower
- Is Hundred Health Worth the $499?
- Is Hundred Health Legit?
- Who Is Hundred Health Best For?
- My Verdict
- Frequently Asked Questions
What Is Hundred Health?
Hundred Health is a direct-to-consumer health optimization platform founded by Tyler Smith that launched publicly in December 2025. The core premise is simple: most annual physicals test 14 to 20 basic markers and send you home with a PDF full of numbers you don't quite know what to do with. Hundred tests over 160 biomarkers across two lab visits per year, then combines those results with your wearable data and a detailed health intake to build a personalized 100-day action plan.

The “100-day” framing is intentional. The company's position is that 100 days is long enough to drive real measurable changes but focused enough to avoid the endless-optimization spiral that derails most health programs. Every 100 days, you retest and update your protocol accordingly.
What separates Hundred from competitors like Function Health and Superpower is the integration layer. Hundred syncs with Oura, Whoop, and Apple Fitness to layer your real-time biometric data on top of your bloodwork, combining continuous wearable data with an advanced biomarker panel into one personalized action plan. That combination is the company's real differentiator, and it is one no competitor at this price point currently matches.
How Hundred Health Works
The process is genuinely simple. Here is exactly how it has unfolded for me:
Step 1: Sign up and complete onboarding. After joining, you work through a detailed health questionnaire in the app. The questions go well beyond a standard health form. The hormone health section asks specifically about perimenopause symptoms, HRT or birth control use, pregnancy and postpartum status, and cycle timing, because context matters enormously for hormone interpretation. The medications screen explains that knowing your prescriptions and OTC medications helps avoid conflicts and ensure safe guidance. This level of clinical nuance is exactly what a standard annual physical skips entirely.
Step 2: Schedule your lab appointment. Hundred partners with Quest Diagnostics. You book directly through the app at one of roughly 5,000 locations nationwide. My booking took a few minutes and I had an early morning slot within days. Quest is reliable and I've always had good experiences there.
Step 3: Complete your blood and urine draw. Both a blood draw and a urine sample are collected at the Quest visit. The urine component is important: a significant portion of Hundred's panel is urinalysis markers that only come from urine. My draw this morning was fast, the phlebotomist was efficient, and I was out in under fifteen minutes.
Step 4: Wait for results. The app shows a “waiting for results” screen with a note that insights will cover stress, energy, inflammation, and metabolism once the sample is processed. Typical turnaround is about a week, though some advanced markers take a few days longer.
Step 5: Receive your 100-day protocol. Once results are in, clinicians review your full biomarker data and generate a personalized protocol with guidance across nutrition, exercise, supplementation, and recovery. The goal is actionable steps, not just a report card.
Step 6: Retest at the midpoint. Your membership includes two testing cycles. At the six-month mark you retest, compare trends, and the protocol updates accordingly. Trend data over time is where this kind of testing really earns its value.
What Does Hundred Health Test? The Full Panel
This is the section I want to be precise about, because vague descriptions like “100+ biomarkers” do not tell you much. Here is what is actually included in the standard Hundred Health membership panel, organized by category. Markers noted with (x2) are tested at both draws.
Heart Health: A genuinely advanced lipid panel covering not just total cholesterol and LDL, but LDL particle number (LDL-P), small LDL particle number, LDL peak size, Apolipoprotein B (ApoB), Lipoprotein(a), HDL, non-HDL cholesterol, and triglycerides. ApoB and Lp(a) are the markers most standard physicals skip, and research consistently shows they are stronger predictors of cardiovascular events than LDL-C alone, particularly relevant for anyone with metabolic concerns or a family history of heart disease.[1]
Female Hormones: Testosterone (total and free), estradiol, progesterone, FSH, LH, SHBG, prolactin, and IGF-1. This is a comprehensive female hormone panel. IGF-1 in particular is a marker most DTC platforms leave out of their standard panel, and it connects to growth hormone status, aging, and body composition. Note: thyroid antibodies are not included in the standard panel, only the core thyroid markers below.
Thyroid Function: TSH, Free T4, Free T3, and Total T4. Solid core thyroid coverage. If you have known thyroid antibody concerns (Hashimoto's, for example), this is worth flagging with the clinical team or considering as a separate add-on test.
Metabolism and Energy: Fasting insulin (x2), glucose (x2), HbA1c (x2), and leptin. The inclusion of leptin is notable: it regulates satiety and energy balance and is a marker that many people struggling with weight despite doing everything “right” have never had checked. Research links leptin resistance to metabolic dysfunction and difficulty maintaining fat loss.[2]
Liver Health: ALT (x2), AST (x2), ALP (x2), GGT, total bilirubin, albumin (x2), total protein, and globulin. A full hepatic panel, important for anyone taking supplements, medications, or following a high-protein or ketogenic dietary approach.
Kidney Health: Creatinine (x2), BUN (x2), BUN/creatinine ratio (x2), eGFR (x2), uric acid, and microalbumin from urine. Testing microalbumin in urine is a meaningful addition: it is an early marker of kidney stress that standard blood panels miss entirely.
Inflammation and Immune System: High-sensitivity CRP (x2), plus a full ANA screen covering antinuclear antibodies titer, pattern, and screen. The ANA panel is a standout inclusion. Antinuclear antibodies are the primary screening tool for autoimmune conditions including lupus, Sjogren's, and mixed connective tissue disease. This is not a marker most DTC platforms include in a standard panel at this price point.
Stress and Aging: Cortisol (x2) and IGF-1. Cortisol tested twice per year gives you a meaningful before-and-after data point on your stress physiology, especially if you are making lifestyle or training changes between draws.
Biological Age: Calculated from a composite of eight markers: white blood cell count (x2), ALP (x2), glucose (x2), lymphocytes (x2), creatinine (x2), MCV (x2), RDW (x2), and albumin (x2). This is not a separate test but a composite score derived from your blood panel, useful as a trend metric over time.
Nutrient Levels: Vitamin D (x2), ferritin (x2), iron (x2), iron binding capacity (TIBC), iron saturation percentage, magnesium, zinc, and homocysteine. Homocysteine is an important inclusion: elevated levels are associated with cardiovascular risk and B vitamin insufficiency, and it is a marker many standard panels skip. One important note: B12 and folate are NOT included in the standard panel. If those are priorities for you, they would need to be ordered separately.
Cancer Detection: PSA total, PSA free, and PSA free percentage. This is included for all members, not just those with a prostate. Women can have detectable PSA as well, and including it adds a layer of screening depth.
Electrolytes and Hydration: Sodium, potassium, chloride, calcium, and carbon dioxide. A complete electrolyte panel, relevant for athletic performance, heart rhythm, and hydration status, and often absent from DTC testing panels.
Pancreas and Digestion: Amylase and lipase. These enzymes screen for pancreatic function, a clinical credibility marker that signals Hundred is not just running a glorified wellness panel.
Toxins and Heavy Metals: Lead. Including a lead level in a standard consumer health panel is genuinely unusual. Given the growing awareness of environmental toxin exposure and its long-term health implications, this is a meaningful addition.
Urinalysis: The urine panel is far more extensive than most people expect. Across both draws, Hundred tests approximately 30 urine markers including protein, glucose, ketones, pH, specific gravity, occult blood, nitrites, leukocyte esterase, bilirubin, creatinine, and a full microscopic sediment analysis covering RBCs, WBCs, casts, crystals, bacteria, yeast, and epithelial cells. This is a clinical-grade urinalysis, not a basic dipstick screen.
Premium Add-Ons: Where It Gets Really Interesting
Beyond the standard panel, Hundred has built out a premium add-on menu of specialty tests that integrate directly into your dashboard and protocol. This is where Hundred starts to look genuinely different from any competitor in the space. Two add-ons are available right now; several more are launching in Q1 2026.
Available Now:
DUTCH Complete ($300). The DUTCH (Dried Urine Test for Comprehensive Hormones) test maps sex hormones, cortisol rhythm, and hormone metabolism pathways in a level of detail that a standard blood panel cannot touch. It shows not just what your hormone levels are, but how your body is processing and clearing them, and that is where the real clinical picture lives. If you are dealing with energy crashes, disrupted sleep, perimenopause symptoms, or stubborn weight despite good habits, the DUTCH is arguably the most informative single test you can do. I have been interested in this test for a while and the fact that it integrates into the Hundred protocol rather than existing as a separate standalone result is a significant advantage.
DNA Methylation Test from TruMe Labs ($180). This tests folate metabolism and neurotransmitter regulation via a panel called Folate 2.0. Methylation is a foundational biochemical process involved in gene expression, detoxification, neurotransmitter synthesis, and cardiovascular health. If you know you carry MTHFR variants or have a family history of conditions linked to methylation dysfunction, this is worth adding. Note: this is not an ApoE genotyping test; if you want ApoE status, that remains a separate add-on through Function Health or your physician.
Coming Q1 2026:
Galleri by GRAIL. I did the Galleri test through Function Health, and given the significant cancer history in my family, it was one of the most meaningful health investments I have made. Galleri is a multi-cancer early detection blood test that screens for signals from 50+ cancer types, including many that have no standard screening protocol, including pancreatic, ovarian, and esophageal cancer. The research behind cell-free DNA cancer detection is compelling: studies show that detecting cancer at stage 1 increases five-year survival rates dramatically compared to stage 3 or 4 detection, which is precisely where most cancer is found today because standard screening does not exist for the majority of cancer types.
Having this available as a Hundred add-on, with results integrated into your health dashboard rather than a separate patient portal, is a meaningful step forward for anyone with a family history that warrants proactive screening.
Prenuvo Full Body MRI. A 60-minute head-to-pelvis MRI with no radiation, designed to detect tumors, aneurysms, organ abnormalities, and 500+ conditions before they cause symptoms. Prenuvo requires a clinic visit at one of their locations in major metro areas. If you are in a city where this is accessible, the combination of Galleri (blood-based cancer signals) and Prenuvo (structural imaging) represents about as comprehensive an early detection approach as exists in consumer medicine right now.
Women's Hormone Deep Dive. A combined bloodwork and DUTCH panel covering estrogen, progesterone, testosterone, thyroid, and stress hormones with context across your cycle or menopausal transition. This is the add-on I am most likely to do next after my standard results come back.
Coronary Calcium Scoring. A CT scan that measures actual calcified plaque in your coronary arteries, one of the strongest predictors of cardiac events available, and one that standard risk calculators based on cholesterol alone frequently miss.
Continuous Glucose Monitor. A two-week CGM wear that shows how your body responds to food, stress, sleep, and exercise in real time. When layered against your wearable data and fasting insulin results from your blood panel, this becomes a comprehensive metabolic picture. I've used CGMs extensively in the past and they're a great tool for health insights. I highly recommend trying a one month trial of a CGM if you've never done it before.
Comprehensive Gut Mapping. DNA sequencing of bacteria, fungi, and pathogens in the microbiome, plus inflammation and digestive markers. Results integrate into your protocol rather than arriving as a standalone report.
The fact that all of these integrate into your Hundred dashboard and protocol rather than being managed across four different patient portals is the real value here. This is the health data fragmentation problem Hundred was built to solve, and the add-on menu is where that vision becomes most concrete.
My First Impressions: The App and Onboarding
The Hundred app is currently in beta, as shown by the label in the top left of the home screen. Given that the company launched three months ago, this is entirely expected, but worth noting for anyone who needs a fully polished experience from day one.
Within that context, the app is genuinely well-organized. The home screen greeted me by name and immediately showed my onboarding progress: Joined, Scheduled lab test, Completed onboarding, all checked, with “Test 100+ biomarkers” as the next step pending my results. The bottom navigation has five tabs: Home, Biomarkers, Protocol, Activity, and Shop. That structure maps cleanly to the full user journey.
The onboarding questionnaire was the most impressive part of the early experience. The hormone health section asked specifically about perimenopause symptoms, current HRT or birth control, post-menopause status, and cycle timing, because as any woman in her 40s knows, hormone values shift significantly across the cycle and interpreting them without that context is clinical noise. The medications screen explained clearly that this information is used to avoid supplement and drug conflicts and ensure safe protocol guidance. These are not generic health app questions. Someone with real clinical knowledge designed this intake flow.
Scheduling the Quest appointment was seamless through the app. The check-in at the lab itself was standard Quest process: order presented, drawn immediately, done in under fifteen minutes. The less friction in that step, the more likely people are to actually follow through, and Hundred keeps it frictionless.
Medical Records Integration: 21 Years of Health History
This is a feature I did not expect to be as impressive as it turned out to be. During onboarding, Hundred connects to your electronic medical records through its integration with over 300 EHR systems. In my case, it synced 21 years of health history going back to April 2004. The app pulled in 894 clinical documents, 64 procedures, 129 test types, 70 conditions, 384 specialist consults, and 55 medications. All of that arrives in a clean summary screen that reads “Your records at a glance.”
Why this matters: when the clinical team builds your 100-day protocol, they are not working from a single blood draw in isolation. They have context on your full medical trajectory, including past diagnoses, procedures, and medication history. That is a fundamentally different starting point than what competitors offer. Function Health now allows manual document uploads, and Superpower lets you upload past lab data, but neither automatically syncs with your EHR systems to pull in your full medical history the way Hundred does.
For someone like me with a significant surgical history and decades of health data across multiple providers, having all of that automatically aggregated in one place is genuinely valuable.
I will note that the app prompted me to confirm what it found after the records import, which is a smart design choice. Automated imports from EHR systems are not always perfectly clean, and giving the user a chance to verify and correct before anything is used clinically shows attention to accuracy.


Early Results: What Came Back First
I completed my blood draw on the morning of March 16, 2026. By the next morning, the app was already showing partial results: 48 of 107 biomarkers back from the lab, climbing to 51 within the hour. That turnaround surprised me. With both Function Health and Superpower, I waited at least a couple of days before seeing any results at all. Hundred appears to push results to the app in real time as individual panels clear the lab, rather than waiting to deliver everything at once. They also send a text to alert you as new results arrive. In about 27 hours I was up to 68.



Among the early results, two markers immediately caught my attention. My iron came back at 181 mcg/L against a reference range of 45 to 160, and my iron saturation was 49% against a range of 16 to 45%. Both flagged as out of range. My TIBC (iron binding capacity) was 371 µg/dL, which is well within the normal range of 250 to 450, so this is not an iron deficiency picture at all. It is the opposite: elevated iron stores and high saturation.
This is exactly the kind of finding that a standard annual physical often misses. Most basic panels check hemoglobin and maybe ferritin, but they do not run a full iron panel with saturation and TIBC. Elevated iron saturation in particular is a marker worth following up on, as it can indicate hemochromatosis (iron overload), excess supplementation, or other conditions that benefit from early intervention. I do not supplement with iron and I eat a whole foods diet with moderate red meat intake, so this is a result I will be discussing with my physician.
What I appreciated about the app experience: each marker comes with a clear explanation, your result displayed against the reference range, and a “Results over time” chart that will become more useful as I accumulate data across draws. The interface is clean and easy to parse even for someone who is not used to reading lab values. For those who are, the actual numbers and units are right there with no simplification that hides clinically relevant detail.
I am still waiting for the remaining results, including hormones, inflammation markers, the ANA panel, and several others that take longer to process. I will continue updating this review as the full picture comes in and once my 100-day protocol is generated.
Hundred Health Pros and Cons
What I like:
- Deep biomarker panel (over 160 tests per year across two draws) including several markers most platforms skip, including ANA, ApoB, Lp(a), leptin, lead, microalbumin, and a full electrolyte panel
- Genuine wearable integration with Oura, Whoop, and Apple Fitness; your biometric data actually informs the protocol, not just a badge feature
- Medical records integration imported 21 years of health history automatically, including 894 clinical documents, giving the clinical team full context for protocol development; no competing platform does this at the same depth
- Results began arriving within 24 hours of my blood draw, with biomarkers populating the app in real time as panels cleared the lab
- Clinician-reviewed 100-day protocol is action-oriented, not just a results dashboard
- Premium add-ons menu is genuinely exciting, particularly the DUTCH Complete and the upcoming Galleri cancer screen
- All add-on results integrate into your dashboard and protocol rather than arriving in separate portals
- Thoughtful, clinically intelligent onboarding with women's hormone context built in
- HSA and FSA eligible
- HIPAA compliant, CLIA certified, CAP accredited, SOC 2 certified, Quest partner
- Supplement access to Thorne and Momentous at up to 20% off with protocol-specific recommendations (or use the links right here for a discount!)
What to consider:
- App is currently in beta; features are evolving and some things may not be fully built out yet
- Company launched December 2025 with no long-term user track record to evaluate yet
- Thyroid antibodies are not included in the standard panel, which is relevant for those with known or suspected autoimmune thyroid conditions
- B12 and folate are not in the standard panel, a notable gap for anyone monitoring those specifically
- No physician-prescribed treatments (HRT, GLP-1s, peptides); Hundred is not a clinical practice and does not replace one
- In-home phlebotomy costs extra; the standard membership price requires a Quest location visit
- Additional lab fees apply for New York and New Jersey members
- Most of the most exciting add-ons (Galleri, Prenuvo, CGM, gut mapping) are not yet available, launching Q1 2026
Hundred Health vs Function Health vs Superpower
I have personally completed both Function Health and Superpower, so this comparison is grounded in real experience. With Function Health I completed two draws (about 12 vials each time, plus a urine sample), received clinician notes on all results, and got a proactive follow-up call from a Function Health physician when a couple of my values came back unusual, and that kind of outreach impressed me. I also did the Galleri multi-cancer early detection test as an add-on through Function, which given my family cancer history was one of the most important health decisions I have made. You can read my full Function Health review and Superpower Health review for the complete picture. Here is how Hundred stacks up:
| Hundred Health | Function Health | Superpower | |
|---|---|---|---|
| Price | $499/year | $499/year | $199-$499/year |
| Tests per year | 160+ (2 draws) | 160+ (2 draws) | 100+ (1-2 draws by tier) |
| Wearable integration | Oura, Whoop, Apple Fitness | None | Limited |
| Medical records import | Yes (300+ EHR systems) | Manual document upload | Upload past labs only |
| Action plan | 100-day clinician-reviewed protocol | Dashboard + clinician notes | Personalized plan + AI chat |
| Cancer screening add-on | Galleri (coming Q1 2026) | Galleri (available now, $899) | Galleri (available) |
| Hormone deep-dive add-on | DUTCH Complete ($300, now) + Women's Deep Dive (Q1 2026) | Add-ons available | Add-ons available |
| Lab network | Quest (5,000 locations) | Quest + LabCorp | Quest (~2,000 locations) |
| HSA/FSA eligible | Yes | Yes | Yes |
| Founded | 2025 | 2021 | 2023 |
The most meaningful practical difference between Hundred and Function Health is wearable integration. If you are already wearing an Oura or Whoop, your sleep scores, HRV, activity, and recovery data should be part of your health protocol, not sitting in a separate app with no connection to your labs. Hundred does this; Function Health does not. That said, Function Health remains a strong platform with real clinical depth, a mature dashboard, and the Mark Hyman functional medicine philosophy behind it. The proactive physician outreach when something looks off was genuinely valuable in my experience. If the wearable integration is not important to you, Function is still a top-tier option.
Versus Superpower: Hundred is more expensive at the base tier but includes two draws and wearable sync that Superpower does not offer. Superpower has a stronger AI chat experience for asking questions about your results and a lower entry price for a one-time baseline snapshot. For an ongoing integrated protocol, Hundred is the more complete choice.
One piece of market context worth knowing: Function Health and Superpower are currently in active federal litigation, with Function filing suit against Superpower in January 2026 over advertising claims. That says something about how competitive this space has become. Hundred is newer and not part of that dispute, but it will need to prove its value through real user outcomes as it scales.
Is Hundred Health Worth the $499?
At $499 per year, Hundred breaks down to about $1.37 per day or roughly $250 per draw. For what is included, that is genuinely competitive.
For comparison: ordering the equivalent panel piecemeal through a direct-to-consumer lab service like Ulta Labs or LabCorp OnDemand would cost $800 to $1,500 or more for comparable depth. A single functional medicine consultation to interpret advanced labs often runs $300 to $500 on its own. At $499 all-in with two draws, clinician protocol review, and wearable integration, the math is straightforward.
The HSA and FSA eligibility is significant. If you have pre-tax health savings funds available, Hundred qualifies. For many people that brings the effective cost considerably lower than the sticker price suggests.
It is also worth noting that Hundred has a referral program: give $25, get $50. If you know someone who is also interested in getting started, the referral credits can further offset the annual membership cost.
The add-ons change the math further. If you are going to do the DUTCH Complete and the Galleri test anyway, and if you have any family history of cancer or hormone dysfunction, both are worth serious consideration, and having them integrate into one platform and one protocol is worth something beyond the individual test prices.
The honest caveat: the value of any biomarker testing service depends entirely on what you do with the results. The 100-day protocol structure is designed to address this directly, giving you actionable guidance rather than just a report card. I will update this review with a full assessment of whether the protocol actually delivers on that promise once my results are in.
Is Hundred Health Legit?
Yes. Hundred Health carries the credentials you want to see from a platform handling sensitive health data and clinical results:
- HIPAA compliant: your health data is handled under federal privacy law
- CLIA certified: Clinical Laboratory Improvement Amendments certification means the lab meets federal quality standards
- CAP accredited: College of American Pathologists accreditation is among the most rigorous quality certifications in lab medicine
- Quest Diagnostics partner: one of the two largest clinical lab networks in the U.S.
- SOC 2 certified: independently audited data security practices
The clinical team includes physicians and researchers with backgrounds in metabolism, longevity, and human health. Every protocol recommendation is clinician-reviewed and grounded in research. The company is based in Sacramento, California and was founded by Tyler Smith, who describes building Hundred after his own biological age results prompted a significant personal health overhaul.
The only real uncertainty at this stage is newness. A sound credential stack does not automatically guarantee that personalized protocol recommendations will be genuinely useful and accurate at scale, and that is something only time and user data will confirm. I am going in with realistic expectations and will report what I actually experience.
Who Is Hundred Health Best For?
Hundred Health is a strong fit if you:
- Already wear an Oura Ring, Whoop, or Apple Watch and want your biometric data to actually inform a health protocol rather than sit in isolation
- Are a health-conscious woman in your 30s, 40s, or 50s who wants a complete picture of your hormones, metabolic health, cardiovascular risk, and inflammatory status rather than a “normal” result from a 14-marker physical
- Are in perimenopause or approaching it and want baseline data before symptoms escalate; the DUTCH Complete add-on makes this platform especially relevant
- Have a family history of cancer and want proactive multi-cancer early detection in your annual health routine; the Galleri add-on arriving Q1 2026 makes this the most accessible way to integrate that testing into a comprehensive health picture
- Have ApoE4 status, a family history of heart disease, or metabolic concerns, where the ApoB, Lp(a), fasting insulin, and leptin markers in the standard panel are directly relevant
- Have used Function Health or Superpower and want to add wearable context and a structured 100-day action plan to your lab testing practice
- Prefer a structured protocol format over an open-ended data dashboard
It is probably not the right fit if you need physician-prescribed interventions like HRT, GLP-1s, or peptides built into the platform; for that, look at Outlive.bio. And if you just want a one-time baseline snapshot without ongoing commitment, Superpower's lower-priced tier is worth considering first.
My Verdict
I am genuinely optimistic about Hundred Health. The biomarker panel is more thorough than I expected and includes several markers that competing platforms at this price point skip, including ANA, ApoB, Lp(a), leptin, lead, microalbumin, a full electrolyte panel, and a clinical-grade urinalysis. The add-on menu, particularly the DUTCH Complete (available now) and Galleri cancer screen (Q1 2026), pushes this well beyond what most DTC health platforms offer. The app is clean and well-organized in beta. The onboarding is clinically intelligent. The draw process was frictionless.
The medical records integration was a standout surprise: 21 years of health history imported automatically, giving the clinical team context that no competing platform matches. And the speed of results, with biomarkers arriving in the app within 24 hours of my draw, sets a new bar for this category. The early out-of-range iron findings are exactly the kind of clinically meaningful flag that justifies this level of testing.
What I cannot tell you yet is whether the 100-day protocol will be genuinely personalized and actionable, or whether it will feel like generic wellness recommendations dressed up with my specific numbers. That question matters most, and I will answer it honestly once my remaining results arrive. I will update this review with a full protocol assessment, biomarker highlights, and whether the wearable integration adds real context to what the labs show.
For now: if you have been thinking about getting serious about biomarker testing and you want a platform that actually connects your wearable data and your labs into one structured action plan, backed by a premium add-on menu that includes the most compelling specialty tests available in consumer health today, Hundred Health is the most integrated option at this price point. I think it is worth the $499.
Check current Hundred Health pricing and availability here.
frequently asked questions
How much does Hundred Health cost?
Hundred Health costs $499 per year, approximately $1.37 per day or $250 per draw. The membership includes two rounds of lab testing per year (160+ biomarkers total), a clinician-reviewed 100-day action plan, wearable integration, and discounted access to Thorne and Momentous supplements. The membership is HSA and FSA eligible. Additional fees apply for in-home phlebotomy and for members in New York and New Jersey due to state regulations.
Does Hundred Health import your medical records?
Yes. During onboarding, Hundred Health syncs with your existing electronic medical records through its integration with over 300 EHR systems. In my case, the app pulled in 21 years of health history spanning 894 clinical documents, 64 procedures, 129 test types, 70 conditions, 384 specialist consults, and 55 medications. This historical context feeds into your protocol so the clinical team is not working from a blank slate. No other DTC biomarker platform I have tested imports this level of medical history automatically.
Is Hundred Health worth it?
For most health-conscious people who want more than a standard annual physical, yes. At $499 per year for 160+ biomarkers across two draws, a clinician-built 100-day protocol, and wearable integration, the value is hard to match. Ordering equivalent panels individually would typically cost $800 to $1,500 or more. The premium add-ons, including the DUTCH Complete hormone test and the upcoming Galleri multi-cancer screen, add further value for those who want deeper specialty testing integrated into one platform. The main caveat is that the company launched in December 2025, so long-term track record data is still being established.
Is Hundred Health legit?
Yes. Hundred Health is HIPAA compliant, CLIA certified, CAP accredited, SOC 2 certified, and partners with Quest Diagnostics for sample collection. All protocols are clinician-reviewed and grounded in clinical research. The company is new (launched December 2025), but the underlying credentials and lab infrastructure are legitimate.
How does Hundred Health compare to Function Health?
Both cost $499 per year and include 160+ biomarkers across two draws. The key difference: Hundred Health integrates with Oura, Whoop, and Apple Fitness to layer wearable data into your protocol. Function Health does not. Function has been operating since 2021 and has a more established track record, plus proactive physician outreach when values look unusual, something I personally experienced and appreciated. Hundred's 100-day protocol structure is more action-oriented than Function's dashboard approach. See my full Function Health review for details.
How does Hundred Health compare to Superpower?
Hundred includes wearable integration that Superpower does not. Superpower has a lower entry price ($199 tier) and a stronger AI chat feature for interpreting your results. Hundred includes two draws per year at the base price; Superpower's base tier includes one. See my full Superpower Health review for more detail.
What biomarkers does Hundred Health test?
The standard panel covers 160+ markers across two annual draws. Key categories include: cardiovascular (ApoB, Lp(a), LDL-P, full lipid panel), metabolic health (fasting insulin twice, glucose twice, HbA1c twice, leptin), female hormones (testosterone total and free, estradiol, progesterone, FSH, LH, SHBG, prolactin, IGF-1), thyroid (TSH, Free T3, Free T4, Total T4; note that thyroid antibodies are not in the standard panel), liver, kidney including urine microalbumin, inflammation (hs-CRP twice plus full ANA autoimmune screen), nutrients (Vitamin D twice, ferritin twice, iron twice, zinc, magnesium, homocysteine; B12 and folate are not included), electrolytes, pancreas enzymes, lead, PSA, biological age composite, cortisol twice, and a comprehensive 30+ marker urinalysis.
What add-ons does Hundred Health offer?
Two add-ons are currently available: the DUTCH Complete hormone test ($300), which maps sex hormones and cortisol rhythm in detail ideal for perimenopause and energy or sleep issues, and a DNA Methylation Test via TruMe Labs ($180) covering folate metabolism and neurotransmitter regulation. Launching Q1 2026: Galleri by GRAIL multi-cancer early detection screen (covers 50+ cancer types), Prenuvo full-body MRI, Women's Hormone Deep Dive, Coronary Calcium Scoring, Continuous Glucose Monitor, Comprehensive Gut Mapping, and Vaginal Microbiome test. All add-on results integrate into your Hundred dashboard and protocol.
Does Hundred Health work with Oura Ring and Whoop?
Yes. Hundred Health integrates with Oura, Whoop, and Apple Fitness to incorporate sleep, HRV, activity, and recovery data into your health profile and 100-day protocol. This is one of Hundred's most meaningful differentiators: no competing platform at this price point connects wearable biometrics and advanced lab testing into one action plan.
Does Hundred Health replace my doctor?
No. Hundred Health is designed to complement your primary care physician, not replace them. It helps you arrive at appointments more informed and gives you a structured plan for what happens between visits. It does not prescribe medications or treatments. If you need physician-guided interventions like HRT, GLP-1s, or peptides, you will need a licensed provider for that





